SCHEMBL7628338

SCHEMBL7628338

O=C1CC(Cc2ccccc2)O1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.53
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
CTRB1 P17538 1/20 0.44
F2 P00734 2/20 0.44
PRSS1 P07477 2/20 0.44
FASN P49327 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8352429 0.80 CYP3A4 (0.60) SLC6A2SLC6A4SLC6A3FASN
SCHEMBL6496581 0.79 GRM2 (0.49) GRM2SLC6A2SLC6A4SLC6A3CTRB1
SCHEMBL14486238 0.79 GRM2 (0.49) GRM2SLC6A2SLC6A4SLC6A3CTRB1
SCHEMBL11377847 0.77 SIGMAR1 (0.66) GRM2
SCHEMBL3142790 0.76 LMNA (0.63)
SCHEMBL12903280 0.76 GLA (0.50) GRM2
SCHEMBL28332415 0.76 GRM2 (0.40) GRM2SLC6A2SLC6A4SLC6A3CTRB1
SCHEMBL19066636 0.76 ABCB1 (0.46) GRM2CTRB1F2PRSS1FASN
SCHEMBL7634585 0.76 GRM2 (0.46) GRM2SLC6A2SLC6A4SLC6A3CTRB1
SCHEMBL28330977 0.76 CASP1 (0.47) GRM2CTRB1F2PRSS1FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same NOVOMER, INC. (US) 2023-11-14 US disclosed
US-11814498-B2 Polylactone foams and methods of making the same NOVOMER, INC. (US) 2023-11-14 US disclosed
US-11814498-B2 Polylactone foams and methods of making the same NOVOMER, INC. (US) 2023-11-14 US disclosed
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same NOVOMER, INC. (US) 2023-11-14 US disclosed
US-20210324168-A1 POLYLACTONE FOAMS AND METHODS OF MAKING THE SAME NOVOMER, INC. 2021-10-21 US disclosed
US-20210277028-A1 METAL-ORGANIC FRAMEWORK CATALYSTS, AND USES THEREOF NOVOMER, INC. 2021-09-09 US disclosed
US-20210221762-A1 SYSTEMS AND PROCESSES FOR PRODUCING ORGANIC ACIDS DIRECTLY FROM BETA-LACTONES NOVOMER, INC. 2021-07-22 US disclosed
US-10961209-B2 Processes for producing beta-lactone and beta-lactone derivatives with heterogenous catalysts NOVOMER, INC. (US) 2021-03-30 US disclosed
US-20200331876-A1 ISOCYANATES, DERIVATIVES, AND PROCESSES FOR PRODUCING THE SAME NOVOMER, INC. 2020-10-22 US disclosed
US-10676426-B2 Acrylonitrile derivatives from epoxide and carbon monoxide reagents NOVOMER, INC. (US) 2020-06-09 US disclosed
CN-109414414-A Method and composition for treating obesity and/or diabetes and for identifying candidate therapeutic agent 戴维·格拉德斯通研究所 2019-03-01 CN disclosed
US-20190047972-A1 PROCESSES FOR PRODUCING BETA-LACTONE AND BETA-LACTONE DERIVATIVES WITH HETEROGENOUS CATALYSTS NOVOMER, INC. (US) 2019-02-14 US disclosed
US-20190002400-A1 Acrylonitrile Derivatives from Epoxide and Carbon Monoxide Reagents NOVOMER, INC. (US) 2019-01-03 US disclosed
US-20190002293-A1 Biobased Carbon Fibers and Carbon Black and Methods of Making the Same NOVOMER, INC. (US) 2019-01-03 US disclosed
WO-2019006366-A1 PROCESS FOR THE PREPARATION OF ORGANIC ACIDS FROM BETA LACTONES NOVOMER, INC. (US) 2019-01-03 WO disclosed
CN-1128819-C Water soluble polymers and their use in cosmetic formulations BASF AG (DE) 2003-11-26 CN disclosed
US-6458348-B1 Use of water-soluble polymers as biocides BASF AKTIENGESELLSCHAFT (DE) 2002-10-01 US disclosed
EP-0915915-B1 WATER SOLUBLE POLYMERS AND THEIR USE IN COSMETIC FORMULATIONS BASF AG (DE) 2001-10-31 EP disclosed
US-6271327-B1 HYDROXYALKYLACRYLIC AMIDES AND DIHYDROXYALKYLACRYLIC IMIDE POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2001-08-07 US disclosed
CN-1232473-A Water-soluble polymers and their use in cosmetic formulations BASF AG (DE) 1999-10-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10676426-B2 Acrylonitrile derivatives from epoxide and carbon monoxide reagents POR, AGL, ALK GRM2 4663/4885SLC6A2 4681/4885SLC6A4 3765/4885
US-20200331876-A1 ISOCYANATES, DERIVATIVES, AND PROCESSES FOR PRODUCING THE SAME IDH1, IDH2, IDH3A GRM2 4460/4885SLC6A2 4883/4885SLC6A4 4832/4885
US-20190002293-A1 Biobased Carbon Fibers and Carbon Black and Methods of Making the Same AGL, CBR1, FASN GRM2 4538/4885SLC6A2 4543/4885SLC6A4 4147/4885
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same IDH1, IDH2, IDH3A GRM2 4460/4885SLC6A2 4883/4885SLC6A4 4832/4885
US-20210277028-A1 METAL-ORGANIC FRAMEWORK CATALYSTS, AND USES THEREOF PPOX, PCCA, MCCC2 GRM2 3200/4885SLC6A2 4880/4885SLC6A4 4785/4885
US-20190002400-A1 Acrylonitrile Derivatives from Epoxide and Carbon Monoxide Reagents POR, AGL, ALK GRM2 4663/4885SLC6A2 4681/4885SLC6A4 3765/4885
US-10961209-B2 Processes for producing beta-lactone and beta-lactone derivatives with heterogenous catalysts AGL, HBZ, RIOX2 GRM2 4050/4885SLC6A2 4857/4885SLC6A4 4779/4885
US-20190047972-A1 PROCESSES FOR PRODUCING BETA-LACTONE AND BETA-LACTONE DERIVATIVES WITH HETEROGENOUS CATALYSTS AGL, HBZ, RIOX2 GRM2 4050/4885SLC6A2 4857/4885SLC6A4 4779/4885
US-20210221762-A1 SYSTEMS AND PROCESSES FOR PRODUCING ORGANIC ACIDS DIRECTLY FROM BETA-LACTONES AGL, FGB, COASY GRM2 1924/4885SLC6A2 4837/4885SLC6A4 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.