Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16244534 | 0.90 | CYP1A2 (0.46) | CYP1A2KDM4EPOLBFAAHKMT2A | |
| SCHEMBL22637340 | 0.88 | CYP1A2 (0.44) | CYP1A2KDM4EPOLBFAAHKMT2A | |
| SCHEMBL31389468 | 0.86 | ALDH1A1 (0.46) | CYP1A2POLBFAAHKMT2A | |
| SCHEMBL20046891 | 0.85 | CYP1A2 (0.42) | CYP1A2KDM4EPOLBFAAHKMT2A | |
| SCHEMBL24958725 | 0.85 | PLAT (0.48) | PLATPOLBKMT2A | |
| SCHEMBL15754077 | 0.84 | ACKR3 (0.42) | CYP1A2KDM4EPOLBFAAH | |
| SCHEMBL20046898 | 0.84 | CYP1A2 (0.41) | CYP1A2KDM4EPOLBFAAHKMT2A | |
| Hydrochloric Acid SCHEMBL2581316 | 0.84 | PLAT (0.47) | PLATKDM4EPOLBKMT2A | |
| SCHEMBL29098496 | 0.83 | PLAT (0.42) | PLATKMT2A | |
| SCHEMBL20722095 | 0.81 | CYP1A2 (0.43) | CYP1A2KDM4EPOLBFAAHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |