Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PAICS | P22234 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2581316 | 0.99 | PLAT (0.47) | PLATKMT2APOLBTDP1PAICS | |
| SCHEMBL13734447 | 0.90 | KMT2A (0.49) | PLATKMT2APOLBTDP1MEN1 | |
| SCHEMBL29098496 | 0.86 | PLAT (0.42) | PLATKMT2APAICSMEN1IRAK4 | |
| SCHEMBL14636109 | 0.85 | PLAT (0.42) | PLATKMT2APOLB | |
| SCHEMBL6388767 | 0.81 | PAICS (0.41) | PLATKMT2ATDP1PAICSMEN1 | |
| SCHEMBL27150682 | 0.81 | KMT2A (0.43) | KMT2APOLBTDP1MEN1NPC1 | |
| SCHEMBL24958742 | 0.79 | KMT2A (0.43) | KMT2APOLBTDP1MEN1NPC1 | |
| SCHEMBL22042066 | 0.79 | KMT2A (0.43) | KMT2APOLBTDP1MEN1NPC1 | |
| SCHEMBL22042043 | 0.79 | KMT2A (0.43) | KMT2APOLBTDP1MEN1NPC1 | |
| SCHEMBL2586290 | 0.78 | GPR119 (0.48) | KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2023-01-26 | — | — | US | disclosed |
| CN-101228156-B | Fungicidal carboxamides | DU PONT | 2012-07-18 | — | — | CN | disclosed |
| CN-101228156-A | Fungicidal carboxamides | DU PONT (US) | 2008-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | PLAT 2059/4885KMT2A 3870/4885POLB 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.