Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426961 | 0.80 | P2RX7 (0.37) | GRIA2 | |
| SCHEMBL2326586 | 0.79 | SMN1; SMN2 (0.47) | CYP3A4KCNH2MAPK1 | |
| SCHEMBL115262 | 0.75 | CYP2A6 (0.38) | FOLH1CYP3A4CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL29790356 | 0.75 | CYP2A6 (0.38) | FOLH1CYP3A4CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL778325 | 0.75 | HTT (0.40) | MMP2MMP9MMP13MMP8 | |
| SCHEMBL2323224 | 0.75 | EPHX2 (0.38) | EPHX2MAPK1 | |
| SCHEMBL25489183 | 0.74 | CYP2A6 (0.36) | FOLH1CYP3A4CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL3513409 | 0.74 | CYP2A6 (0.36) | FOLH1CYP3A4CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL30144069 | 0.74 | CYP2A6 (0.36) | FOLH1CYP3A4CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL29009823 | 0.73 | PTGS2 (0.47) | FOLH1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734505-A1 | 3-(FLUORVINYL)PYRAZOLES AND THE USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2014-05-28 | — | — | EP | disclosed |
| WO-2013011033-A1 | 3-(FLUORVINYL)PYRAZOLES AND THE USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-24 | — | — | WO | disclosed |