SCHEMBL14636199

SCHEMBL14636199

C=CCc1csc2cc3c(CC=C)csc3cc12

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
CYP2A6 P11509 5/20 0.35
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23009186 0.81 CYP2A6 (0.33) GABRA1GABRB2CYP2A6
SCHEMBL4539007 0.79 CYP2A6 (0.31) CYP2A6
SCHEMBL3257224 0.78 CYP2A6 (0.60) CYP2A6
SCHEMBL1595423 0.72 GABRA1 (0.35) GABRA1GABRB2POLB
SCHEMBL1594814 0.69 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL601135 0.68 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL44699 0.67 GABRA1 (0.48) GABRA1GABRB2POLB
Hydrochloric Acid SCHEMBL1386239 0.67
SCHEMBL29113072 0.66 CYP2A6 (0.39) CYP2A6
SCHEMBL3226473 0.66 GABRA1 (0.38) GABRA1GABRB2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2734527-B1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2018-01-10 EP disclosed
US-9577197-B2 Conjugated polymers MERCK PATENT GMBH (DE) 2017-02-21 US disclosed
US-9577197-B2 Conjugated polymers MERCK PATENT GMBH (DE) 2017-02-21 US disclosed
US-20140175339-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2014-06-26 US disclosed
US-20140175339-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2014-06-26 US disclosed
EP-2734527-A1 CONJUGATED POLYMERS Merck Patent GmbH (DE) 2014-05-28 EP disclosed
EP-2734527-A1 CONJUGATED POLYMERS Merck Patent GmbH (DE) 2014-05-28 EP disclosed
CN-103687861-A Conjugated polymers MERCK PATENT GMBH 2014-03-26 CN disclosed
WO-2013010615-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2013-01-24 WO disclosed
WO-2013010615-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2013-01-24 WO disclosed