Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1595423 | 0.75 | GABRA1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL3226473 | 0.69 | GABRA1 (0.38) | GABRA1GABRB2 | |
| SCHEMBL14636199 | 0.68 | GABRA1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL2577555 | 0.68 | ALDH1A1 (0.32) | GABRA1GABRB2 | |
| SCHEMBL1386242 | 0.67 | — | — | |
| SCHEMBL11883373 | 0.67 | DHFR (0.32) | GABRA1GABRB2 | |
| SCHEMBL9387535 | 0.66 | GABRA1 (0.44) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL1386239 | 0.66 | — | — | |
| SCHEMBL4539007 | 0.66 | CYP2A6 (0.31) | — | |
| SCHEMBL1594814 | 0.64 | GABRA1 (0.32) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778695-B1 | POLYMERS OF THIENO[2,3-b]THIOPHENE | MERCK PATENT GMBH (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-8114316-B2 | Monomers, oligomers and polymers of thieno[2,3-b]thiophene | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20090072200-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF THIENO[2,3-b]THIOPHENE | FLEXENABLE TECHNOLOGY LIMITED (GB) | 2009-03-19 | — | — | US | disclosed |
| EP-1778695-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF THIENO[2,3-b]THIOPHENE | Merck Patent GmbH (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006021277-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF THIENO[2,3-b]THIOPHENE | MERCK PATENT GMBH (DE) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090072200-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF THIENO[2,3-b]THIOPHENE | FHIT, NLRP3, RFT1 | GABRA1 4234/4885GABRB2 3254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.