Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | NMBR | P28336 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14654947 | 1.00 | NPC1 (0.63) | NPC1RAB9ALMNATAAR1ALDH1A1 | |
| SCHEMBL11745735 | 0.86 | NPC1 (0.65) | NPC1RAB9ALMNATAAR1KMT2A | |
| SCHEMBL21950095 | 0.86 | NPC1 (0.65) | NPC1RAB9ALMNATAAR1KMT2A | |
| SCHEMBL4033719 | 0.86 | NPC1 (0.65) | NPC1RAB9ALMNATAAR1ALDH1A1 | |
| SCHEMBL13534727 | 0.86 | NPC1 (0.65) | NPC1RAB9ALMNATAAR1ALDH1A1 | |
| SCHEMBL12497357 | 0.85 | ITGB3 (0.57) | ALDH1A1 | |
| SCHEMBL9554401 | 0.85 | ITGB3 (0.57) | ALDH1A1 | |
| SCHEMBL18190836 | 0.85 | ITGB3 (0.57) | ALDH1A1 | |
| SCHEMBL21921542 | 0.84 | NPC1 (0.63) | NPC1RAB9ALMNATAAR1ALDH1A1 | |
| SCHEMBL4583554 | 0.84 | CYP3A4 (0.61) | NPC1RAB9ALMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013011526-A1 | PROCESS FOR PREPARATION OF LISDEXAMPHETAMINE AND SALTS THEREOF | IND-SWIFT LABORATORIES LIMITED (IN) | 2013-01-24 | — | — | WO | disclosed |