SCHEMBL4033719

SCHEMBL4033719

CC(Cc1ccccc1)NC(=O)OCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.65
RAB9A P51151 1/20 0.65
CTRB1 P17538 2/20 0.64
ATM Q13315 1/20 0.59
CTSK P43235 3/20 0.59
CTSL P07711 2/20 0.59
CTSS P25774 2/20 0.59
CTSB P07858 1/20 0.59
TRPM8 Q7Z2W7 1/20 0.58
ALDH1A1 P00352 1/20 0.58
ALOX15 P16050 1/20 0.58
TACR1 P25103 2/20 0.57
LMNA P02545 1/20 0.56
ELANE P08246 1/20 0.56
TAAR1 Q96RJ0 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13534727 1.00 NPC1 (0.65) NPC1RAB9ACTRB1ATMCTSK
SCHEMBL9707035 0.94 CTRB1 (0.58) NPC1RAB9ACTRB1ATMCTSK
SCHEMBL9782114 0.94 CTRB1 (0.58) NPC1RAB9ACTRB1ATMCTSK
SCHEMBL13884452 0.93 CTRB1 (0.57) NPC1RAB9ACTRB1ATMCTSK
SCHEMBL14884509 0.93 CTRB1 (0.57) NPC1RAB9ACTRB1ATMCTSK
Cyclopentane SCHEMBL8925976 0.93 CTRB1 (0.57) NPC1RAB9ACTRB1ATMCTSK
SCHEMBL15082424 0.92 CTRB1 (0.56) NPC1RAB9ACTRB1ATMCTSK
SCHEMBL10305326 0.92 CTRB1 (0.56) NPC1RAB9ACTRB1ATMCTSK
SCHEMBL12193558 0.92 NPC1 (0.63) NPC1RAB9ACTRB1ATMCTSK
SCHEMBL29137641 0.90 ATM (0.65) NPC1RAB9ACTRB1ATMCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592436-A4 COMPOUNDS THAT BIND P2Y sb 2 /sb OR P2Y sb 1 /sb RECEPTORS KIMBERLY CLARK CO (US) 2009-09-02 EP claimed
EP-1592436-A2 COMPOUNDS THAT BIND P2Y sb 2 /sb OR P2Y sb 1 /sb RECEPTORS Kimberly-Clark Worldwide, Inc. (US) 2005-11-09 EP claimed
WO-2004060907-A2 COMPOUNDS THAT BIND P2Y2 OR P2Y1 RECEPTORS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2004-07-22 WO claimed