Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701263 | 0.85 | MAPT (0.54) | MEN1KMT2AMAPTKLK7KLK5 | |
| SCHEMBL5311249 | 0.83 | MAPT (0.52) | CTSKMAPTKLK7KLK5 | |
| SCHEMBL7977011 | 0.82 | CA1 (0.43) | CTSKCTSSJAK3BTK | |
| SCHEMBL18942773 | 0.82 | MAPT (0.64) | MAPTKLK7KLK5 | |
| SCHEMBL24095930 | 0.81 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL5307802 | 0.80 | SYK (0.49) | CTSKMMP1MMP3MMP9MAPT | |
| SCHEMBL7549143 | 0.80 | KLK7 (0.64) | CTSKMEN1KMT2AMAPTKLK7 | |
| SCHEMBL7943183 | 0.79 | JAK3 (0.62) | JAK3BTKMAPTKLK7KLK5 | |
| SCHEMBL7943185 | 0.79 | JAK3 (0.62) | JAK3BTKMAPTKLK7KLK5 | |
| SCHEMBL17646424 | 0.79 | JAK3 (0.62) | JAK3BTKMAPTKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013011526-A1 | PROCESS FOR PREPARATION OF LISDEXAMPHETAMINE AND SALTS THEREOF | IND-SWIFT LABORATORIES LIMITED (IN) | 2013-01-24 | — | — | WO | disclosed |