Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20303735 | 0.87 | OPRK1 (0.32) | OPRK1OPRM1LMNAATML3MBTL1 | |
| SCHEMBL1564313 | 0.71 | ALDH1A1 (0.35) | LMNARAB9ASMN1; SMN2 | |
| SCHEMBL14636380 | 0.68 | — | — | |
| SCHEMBL14635669 | 0.68 | — | — | |
| SCHEMBL25940926 | 0.67 | ATM (0.32) | ATML3MBTL1 | |
| SCHEMBL20303774 | 0.66 | — | — | |
| SCHEMBL20221265 | 0.66 | HRH3 (0.35) | ATML3MBTL1 | |
| SCHEMBL711832 | 0.66 | ATM (0.34) | OPRK1LMNAATML3MBTL1SMN1; SMN2 | |
| SCHEMBL14635529 | 0.65 | — | — | |
| SCHEMBL9610 | 0.65 | ATM (0.33) | OPRK1LMNAATML3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |