Dimethylformamide

Dimethylformamide

SCHEMBL14636376

CC(O)CN.CN(C)C=O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALOX15 P16050 2/20 0.31
GABBR2 O75899 2/20 0.31
GABBR1 Q9UBS5 2/20 0.31
USP2 O75604 1/20 0.31
GABRR1 P24046 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL27923056 0.84 ALDH1A1 (0.32) TSHRALDH1A1TDP1GABBR2GABBR1
Butanol SCHEMBL18249458 0.81 TSHR (0.56) TSHRALDH1A1TDP1ALOX15USP2
Propylene Glycol SCHEMBL28137109 0.81 TDP1 (0.56) TSHRALDH1A1TDP1ALOX15USP2
Formic Acid SCHEMBL30166488 0.80 ALDH1A1 (0.37) TSHRALDH1A1TDP1GABBR2GABBR1
Formic Acid SCHEMBL10635397 0.80
Dimethylformamide SCHEMBL28247650 0.80
Dimethylformamide SCHEMBL5861397 0.80
Trimethylammonium SCHEMBL27738013 0.80
Formic Acid SCHEMBL27128879 0.78
Dimethylformamide SCHEMBL277527 0.77 TSHR (0.45) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2734499-A1 MEROCYANINE DERIVATIVES BASF SE (DE) 2014-05-28 EP disclosed
WO-2013011480-A1 MEROCYANINE DERIVATIVES BASF SE (DE) 2013-01-24 WO disclosed