Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL4940105 | 0.81 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL1979 | 0.78 | — | — | |
| Dimethylformamide SCHEMBL14636376 | 0.77 | TSHR (0.47) | TSHRALDH1A1 | |
| SCHEMBL4787789 | 0.75 | ALDH1A1 (0.39) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL366444 | 0.74 | ALDH1A1 (0.44) | ALDH1A1 | |
| Fluoride SCHEMBL1025918 | 0.74 | ALDH1A1 (0.44) | ALDH1A1 | |
| Bromide SCHEMBL1999327 | 0.74 | ALDH1A1 (0.44) | ALDH1A1 | |
| Fluoride SCHEMBL73856 | 0.74 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL3210302 | 0.74 | ALDH1A1 (0.44) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL6136995 | 0.74 | ALDH1A1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2255201-A2 | FLUORESCENCE POLARIZATION HERG ASSAY | Life Technologies Corporation (US) | 2010-12-01 | — | — | EP | claimed |
| US-20090253148-A1 | FLUORESCENCE POLARIZATION hERG ASSAY | Life Technologies Corporation (US) | 2009-10-08 | — | — | US | claimed |
| WO-2009108905-A2 | FLUORESCENCE POLARIZATION HERG ASSAY | Life Technologies Corporation (US) | 2009-09-03 | — | — | WO | claimed |
| EP-2255201-B1 | FLUORESCENCE POLARIZATION HERG ASSAY | LIFE TECHNOLOGIES CORP (US) | 2014-08-06 | — | — | EP | disclosed |
| US-20120231541-A1 | FLUORESCENCE POLARIZATION hERG ASSAY | Life Technologies Corporation (US) | 2012-09-13 | — | — | US | disclosed |
| US-8133695-B2 | Fluorescence polarization hERG assay | Life Technologies Corporation (US) | 2012-03-13 | — | — | US | disclosed |
| EP-2255201-A2 | FLUORESCENCE POLARIZATION HERG ASSAY | Life Technologies Corporation (US) | 2010-12-01 | — | — | EP | disclosed |
| US-20090253148-A1 | FLUORESCENCE POLARIZATION hERG ASSAY | Life Technologies Corporation (US) | 2009-10-08 | — | — | US | disclosed |
| WO-2009108905-A2 | FLUORESCENCE POLARIZATION HERG ASSAY | Life Technologies Corporation (US) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253148-A1 | FLUORESCENCE POLARIZATION hERG ASSAY | TNNI3, TNNT2, KCNQ1 | TSHR 1889/4885ALDH1A1 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.