Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635580 | 0.79 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL14636547 | 0.79 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL21332769 | 0.70 | PI4KA (0.39) | — | |
| SCHEMBL10830950 | 0.70 | BCHE (0.54) | SIGMAR1 | |
| SCHEMBL14636643 | 0.68 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL14630638 | 0.68 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL15703420 | 0.67 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL14636070 | 0.67 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL15703455 | 0.65 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL15703348 | 0.65 | SIGMAR1 (1.00) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734524-A1 | PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS, THEIR PREPARATION AND USE AS SIGMA LIGANDS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2014-05-28 | — | — | EP | disclosed |
| WO-2013010950-A1 | PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS, THEIR PREPARATION AND USE AS SIGMA LIGANDS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2013-01-24 | — | — | WO | disclosed |