SCHEMBL1463728

SCHEMBL1463728

O=C(O)C1CC1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1463730 1.00
SCHEMBL7186214 1.00
SCHEMBL1707149 1.00
SCHEMBL9941707 1.00
SCHEMBL8932029 1.00
SCHEMBL1578014 1.00
SCHEMBL24868052 1.00
SCHEMBL18398206 1.00
SCHEMBL11939917 1.00
Hydrochloric Acid SCHEMBL28405061 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504397-A Synthesis method of 2-fluorocyclopropane carboxylic acid 上海裕兰生物科技有限公司 2025-02-25 CN claimed
CN-110016006-B Azacarboside chalcone and preparation method thereof 合肥亘舒科技有限公司 2021-01-12 CN claimed
CN-108911972-B Racemization recovery method for by-product in resolution mother liquor of sitafloxacin intermediate 武汉大学 2020-07-10 CN claimed
US-10385000-B2 Method for synthesizing 2-fluorocyclopropane carboxylic acid CHEN-STONE (GUANGZHOU) CO., LTD. (CN) 2019-08-20 US claimed
US-20180370893-A1 NEW METHOD FOR SYNTHESIZING 2-FLUOROCYCLOPROPANE CARBOXYLIC ACID CHEN-STONE (GUANGZHOU) CO., LTD. (CN) 2018-12-27 US claimed
EP-2651899-B1 SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF HOFFMANN LA ROCHE (CH) 2017-05-31 EP claimed
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2015-11-12 US claimed
EP-2892343-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS Bayer CropScience AG (DE) 2015-07-15 EP claimed
WO-2014037349-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2014-03-13 WO claimed
US-8623889-B2 Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof GENENTECH, INC. (US) 2014-01-07 US claimed
WO-2013007765-A1 FUSED TRICYCLIC COMPOUNDS FOR USE AS INHIBITORS OF JANUS KINASES F. HOFFMANN-LA ROCHE AG (CH) 2013-01-17 WO claimed
US-7199260-B2 Process for reductive dehalogenation DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-04-03 US claimed
EP-0743299-B1 Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts BAYER AG (DE) 1999-09-15 EP claimed
EP-0726244-B1 Process for producing 2-fluorocyclopropanecarboxylic acid SUMITOMO CHEMICAL CO (JP) 1998-08-12 EP claimed
US-5770767-A Process for producing 2-fluorocyclopropancecarboxlic acid SUMITOMO CHEMICAL COMPANY LIMITED. (JP) 1998-06-23 US claimed
CN-1147504-A Process for preparation of 2-fluorocyclopropylamine sulfonic acid salts and chemical compound 2-fluorocyclopropyl isocyanate BAYER AG (DE) 1997-04-16 CN claimed
EP-0755913-A1 Process for preparing of 2,4-dibromo-4- and -3-fluorobutanoic acid as well as their derivatives BAYER AG (DE) 1997-01-29 EP claimed
EP-0726244-A1 Process for producing 2-fluorocyclopropanecarboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-08-14 EP claimed
JP-8268956-A None JP disclosed
US-3936462-A CNS DEPRESSANT, ANALGESIC STERLING DRUG INC. (US) 1976-02-03 US disclosed