SCHEMBL1707149

SCHEMBL1707149

O=C(O)[C@@H]1C[C@H]1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1463730 1.00
SCHEMBL7186214 1.00
SCHEMBL9941707 1.00
SCHEMBL8932029 1.00
SCHEMBL1578014 1.00
SCHEMBL24868052 1.00
SCHEMBL18398206 1.00
SCHEMBL1463728 1.00
SCHEMBL11939917 1.00
Hydrochloric Acid SCHEMBL28405061 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743299-B1 Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts BAYER AG (DE) 1999-09-15 EP claimed
EP-0755913-A1 Process for preparing of 2,4-dibromo-4- and -3-fluorobutanoic acid as well as their derivatives BAYER AG (DE) 1997-01-29 EP claimed
EP-0743299-A1 Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts and the chemical compound 2-fluorocyclopropylisocyanate BAYER AG (DE) 1996-11-20 EP claimed
JP-11228491-A None JP disclosed
WO-2026107328-A1 AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS SEPTERNA, INC. (US) 2026-05-21 WO disclosed
EP-4029868-B1 MCL-1 INHIBITORS GILEAD SCIENCES INC (US) 2026-05-20 EP disclosed
CN-116829545-B Substituted pyrazolylpiperidine carboxylic acids 拜耳公司 2026-05-15 CN disclosed
US-20260125386-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF KRAS THERAS INC (US) 2026-05-07 US disclosed
US-12559462-B2 Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-20260042764-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF KRAS THERAS INC (US) 2026-02-12 US disclosed
US-20260027108-A1 PHARMACEUTICAL COMPOSITION OF HETEROARYL DERIVATIVE AND MEDICAL USE THEREOF HAISCO PHARMACEUTICAL GROUP CO LTD (CN) 2026-01-29 US disclosed
WO-2010142752-A1 JANUS KINASE INHIBITOR COMPOUNDS AND METHODS F. HOFFMANN-LA ROCHE AG (CH) 2010-12-16 WO disclosed
WO-2010138589-A1 BICYCLIC PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE GENENTECH, INC. (US) 2010-12-02 WO disclosed
US-20100305096-A1 BICYCLIC PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE GENENTECH, INC. 2010-12-02 US disclosed
US-6130350-A Process for producing 2-fluorine-1-cyclopropane carboxylic acid derivatives by reductive dehalogenation BAYER AKTIENGESELLSCHAFT (DE) 2000-10-10 US disclosed
JP-H11228491-A SEPARATION OF CIS/TRANS ISOMER MIXTURE OF 2-FLUOROCYCLOPROPANECARBOXYLIC ACID SUMITOMO CHEM CO LTD 1999-08-24 JP disclosed
EP-0726244-B1 Process for producing 2-fluorocyclopropanecarboxylic acid SUMITOMO CHEMICAL CO (JP) 1998-08-12 EP disclosed
US-5770767-A Process for producing 2-fluorocyclopropancecarboxlic acid SUMITOMO CHEMICAL COMPANY LIMITED. (JP) 1998-06-23 US disclosed
EP-0755913-A1 Process for preparing of 2,4-dibromo-4- and -3-fluorobutanoic acid as well as their derivatives BAYER AG (DE) 1997-01-29 EP disclosed
EP-0726244-A1 Process for producing 2-fluorocyclopropanecarboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-08-14 EP disclosed