SCHEMBL8932029

SCHEMBL8932029

O=C(O)[C@H]1C[C@@H]1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1463730 1.00
SCHEMBL7186214 1.00
SCHEMBL1707149 1.00
SCHEMBL9941707 1.00
SCHEMBL1578014 1.00
SCHEMBL24868052 1.00
SCHEMBL18398206 1.00
SCHEMBL1463728 1.00
SCHEMBL11939917 1.00
Hydrochloric Acid SCHEMBL28405061 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115838329-A Method for synthesizing (1R, 2S) -2-fluoro-cyclopropanecarboxylic acid 邯郸市瑞田农药有限公司 2023-03-24 CN claimed
EP-0755913-A1 Process for preparing of 2,4-dibromo-4- and -3-fluorobutanoic acid as well as their derivatives BAYER AG (DE) 1997-01-29 EP claimed
EP-3704090-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-05-27 EP disclosed
US-12637461-B2 Compounds for the activation of AMPK PFIZER INC. (US) 2026-05-26 US disclosed
WO-2026107328-A1 AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS SEPTERNA, INC. (US) 2026-05-21 WO disclosed
US-20260085034-A1 N-(BENZHYDRYL)CYCLOALKYLCARBOXAMIDE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2026-03-26 US disclosed
EP-4638436-A1 PRMT5 INHIBITORS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2025-10-29 EP disclosed
EP-4635944-A1 2-AZABICYCLO[3.1.1]HEPTANE COMPOUND Daiichi Sankyo Company, Limited (JP) 2025-10-22 EP disclosed
US-20250313556-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS RETUNE PHARMA, INC. 2025-10-09 US disclosed
US-20250304600-A1 PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS AS c-KIT KINASE INHIBITORS ENANTA PHARMACEUTICALS, INC. 2025-10-02 US disclosed
US-20250268877-A1 2H-INDAZOLE DERIVATIVES AS IRAK4 INHIBITORS AND THEIR USE IN THE TREATMENT OF DISEASE BIOGEN MA INC. 2025-08-28 US disclosed
US-9199981-B2 Compounds and compositions as C-kit kinase inhibitors NOVARTIS AG (CH) 2015-12-01 US disclosed
US-20140088076-A1 SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2014-03-27 US disclosed
US-8623889-B2 Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof GENENTECH, INC. (US) 2014-01-07 US disclosed
WO-2013033070-A1 COMPOUNDS AND COMPOSITIONS AS c-KIT KINASE INHIBITORS IRM LLC (BM) 2013-03-07 WO disclosed
US-20130059846-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS IRM LLC (BM) 2013-03-07 US disclosed
US-20130059846-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS IRM LLC (BM) 2013-03-07 US disclosed
US-20120322785-A1 SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2012-12-20 US disclosed
EP-0755913-A1 Process for preparing of 2,4-dibromo-4- and -3-fluorobutanoic acid as well as their derivatives BAYER AG (DE) 1997-01-29 EP disclosed
EP-0755913-A1 Process for preparing of 2,4-dibromo-4- and -3-fluorobutanoic acid as well as their derivatives BAYER AG (DE) 1997-01-29 EP disclosed