Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24007613 | 0.87 | STS (0.44) | STSNR3C1GPR119KDM4EMAPT | |
| SCHEMBL24007025 | 0.84 | TRPV4 (0.41) | KDM4EHPGDEPHX2 | |
| SCHEMBL23546359 | 0.83 | GPR119 (0.45) | NR3C1GPR119KDM4EMAPTTHRB | |
| SCHEMBL24007607 | 0.82 | GPR119 (0.42) | STSNR3C1GPR119KDM4EMAPT | |
| SCHEMBL24880479 | 0.78 | GPR119 (0.46) | NR3C1GPR119KDM4EMAPTTHRB | |
| SCHEMBL31465919 | 0.78 | GPR119 (0.55) | NR3C1GPR119KDM4EPTPN2PTPN1 | |
| SCHEMBL24007611 | 0.78 | STS (0.49) | STSNR3C1GPR119KDM4EMAPT | |
| SCHEMBL18403235 | 0.78 | KDM4E (0.48) | GPR119KDM4EMAPTTHRBKMT2A | |
| SCHEMBL5066894 | 0.77 | STS (0.46) | STSNR3C1GPR119KDM4EMAPT | |
| SCHEMBL23546379 | 0.76 | GPR119 (0.48) | NR3C1GPR119KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |