SCHEMBL14637342

SCHEMBL14637342

CC(C)(C)c1ccc(CCc2nc(Oc3nc(CCc4ccc(C(C)(C)C)cc4)nc4ccccc34)c3ccccc3n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.40
TP53 P04637 2/20 0.40
TNKS O95271 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
LMNA P02545 3/20 0.39
HTT P42858 2/20 0.39
POLB P06746 1/20 0.38
ESRRG P62508 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.38
HPGD P15428 2/20 0.37
SIGMAR1 Q99720 2/20 0.37
TNF P01375 1/20 0.37
NOD1 Q9Y239 1/20 0.37
RAB9A P51151 1/20 0.37
TMEM97 Q5BJF2 1/20 0.37
NR1I2 O75469 1/20 0.36
ADRA2A P08913 1/20 0.36
CYP2D6 P10635 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4887452 0.74 TNF (0.40) SMN1; SMN2TP53TNKSTNKS2LMNA
SCHEMBL11938502 0.73 PPARG (0.39) SMN1; SMN2TP53TNKSTNKS2LMNA
SCHEMBL3847720 0.73 PPARG (0.39) SMN1; SMN2TP53TNKSTNKS2LMNA
SCHEMBL11946803 0.73 HRH4 (0.39) SMN1; SMN2TP53TNKSTNKS2LMNA
SCHEMBL11946802 0.73 POLB (0.39) SMN1; SMN2TP53TNKSTNKS2LMNA
SCHEMBL6547537 0.72 RAB9A (0.56) LMNAPOLBESRRGSIGMAR1RAB9A
SCHEMBL8547647 0.71 CCNB2 (0.43) SMN1; SMN2TP53TNKSTNKS2LMNA
Fenazaquin SCHEMBL29429249 0.70 RAB9A (0.54) MAPK1SMN1; SMN2LMNAHTTPOLB
Fenazaquin SCHEMBL26216 0.70 RAB9A (0.54) MAPK1SMN1; SMN2LMNAHTTPOLB
SCHEMBL8547995 0.69 RAB9A (0.52) MAPK1SMN1; SMN2LMNAHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2734045-B1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL CO (JP) 2016-12-28 EP disclosed
US-8981091-B2 Pest control composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-17 US disclosed
US-20140187778-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-03 US disclosed
EP-2734045-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Company, Limited (JP) 2014-05-28 EP disclosed
WO-2013012099-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-24 WO disclosed