Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14637342 | 0.74 | MAPK1 (0.44) | TNFNOD1TP53SMN1; SMN2POLB | |
| SCHEMBL857320 | 0.72 | KDM4E (0.37) | SMN1; SMN2POLBMEN1KMT2ATNKS2 | |
| SCHEMBL6547537 | 0.69 | RAB9A (0.56) | POLBESRRGSIGMAR1KCNH2LMNA | |
| SCHEMBL7456580 | 0.69 | KCNH2 (0.59) | TP53ESRRGSIGMAR1KCNH2LMNA | |
| SCHEMBL27262014 | 0.64 | KCNH2 (0.50) | ESRRGSIGMAR1KCNH2COPS5DAO | |
| SCHEMBL3022509 | 0.63 | KCNH2 (0.58) | ESRRGSIGMAR1KCNH2LMNAHTR2A | |
| SCHEMBL857662 | 0.63 | LMNA (0.39) | POLBMEN1KMT2ATNKS2LMNA | |
| SCHEMBL9343254 | 0.62 | PDE10A (0.39) | TNFNOD1TP53SMN1; SMN2MEN1 | |
| SCHEMBL31573982 | 0.61 | KCNH2 (0.67) | TP53ESRRGSIGMAR1KCNH2LMNA | |
| SCHEMBL6931652 | 0.61 | RAB9A (0.51) | POLBESRRGKCNH2LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160044922-A1 | Control of Ectoparasites | BAYER ANIMAL HEALTH GMBH | 2016-02-18 | — | — | US | disclosed |
| US-8747877-B2 | Control of ectoparasites | MONSANTO TECHNOLOGY LLC (US) | 2014-06-10 | — | — | US | disclosed |
| US-20080306095-A1 | Control of Ectoparasites | MONSANTO TECHNOLOGY LLC | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160044922-A1 | Control of Ectoparasites | TYR, EPX, PIGO | TNF 4232/4885NOD1 1484/4885TP53 3802/4885 |
| US-20080306095-A1 | Control of Ectoparasites | TYR, EPX, PIGO | TNF 4438/4885NOD1 907/4885TP53 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.