Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3850394 | 0.81 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1NPSR1POLB | |
| SCHEMBL4071588 | 0.79 | LMNA (0.77) | MEN1KMT2AALDH1A1NPSR1POLB | |
| SCHEMBL7125294 | 0.76 | KMT2A (0.58) | MEN1KMT2AALDH1A1NPSR1POLB | |
| SCHEMBL10961901 | 0.72 | PTPN1 (0.70) | MEN1KMT2AALDH1A1NPSR1POLB | |
| SCHEMBL4824728 | 0.71 | POLB (0.73) | MEN1KMT2AALDH1A1NPSR1POLB | |
| SCHEMBL7125293 | 0.71 | PLAU (0.59) | MEN1KMT2AALDH1A1NPSR1POLB | |
| SCHEMBL18221898 | 0.71 | CA12 (0.60) | MEN1KMT2AALDH1A1POLBCYP1A2 | |
| SCHEMBL14515787 | 0.71 | AR (0.56) | MEN1KMT2AALDH1A1NPSR1POLB | |
| SCHEMBL5139062 | 0.71 | AOC3 (0.51) | MEN1KMT2AALDH1A1POLBCYP1A2 | |
| SCHEMBL4068451 | 0.71 | POLB (0.78) | MEN1KMT2AALDH1A1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013011485-A1 | PROCESS FOR THE PREPARATION OF SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2013-01-24 | — | — | WO | disclosed |