Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15011668 | 0.91 | MAPT (0.39) | ABCC4MAPTALDH1A1 | |
| SCHEMBL15103182 | 0.84 | MAPT (0.47) | ABCC4MAPTALDH1A1 | |
| SCHEMBL2493116 | 0.81 | CA12 (0.41) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL4720676 | 0.80 | ALDH1A1 (0.45) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL621722 | 0.78 | CA12 (0.39) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL6898838 | 0.74 | ALDH1A1 (0.34) | MAPTALDH1A1CA12CA1CA9 | |
| SCHEMBL6247927 | 0.72 | CAMK2A (0.38) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL27718087 | 0.72 | MAPT (0.39) | ABCC4MAPTALDH1A1 | |
| SCHEMBL6883197 | 0.72 | CA12 (0.35) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL12888853 | 0.71 | ALDH1A1 (0.50) | ABCC4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013013240-A2 | MACROCYCLIC COMPOUNDS AND RELATED COMPOSITONS AND METHODS OF USE | THERACRINE, INC. (US) | 2013-01-24 | — | — | WO | disclosed |