Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493116 | 0.97 | CA12 (0.41) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8982384 | 0.87 | MAPT (0.50) | CA12CA1CA2CA9MAPT | |
| SCHEMBL6883197 | 0.86 | CA12 (0.35) | CA12CA1CA2CA9MAPT | |
| SCHEMBL6247927 | 0.86 | CAMK2A (0.38) | CA12CA1CA2CA9MAPT | |
| SCHEMBL11512646 | 0.85 | — | — | |
| SCHEMBL4281077 | 0.84 | CA12 (0.33) | CA12CA1CA2CA9MAPT | |
| SCHEMBL6246329 | 0.84 | GPR84 (0.39) | CA12CA1CA2CA9MAPT | |
| SCHEMBL77048 | 0.84 | CA12 (0.46) | CA12CA1CA2CA9MAPT | |
| SCHEMBL3510313 | 0.84 | ALDH1A1 (0.33) | CA12CA1CA2CA9MAPT | |
| Diethanolamine SCHEMBL1696414 | 0.82 | REN (0.36) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210252156-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | HERON THERAPEUTICS INC (US) | 2021-08-19 | — | — | US | disclosed |
| EP-3834817-A1 | SEMI-SOLID DELIVERY VEHICLE AND PHARMACEUTICAL COMPOSITIONS | Heron Therapeutics, Inc. (US) | 2021-06-16 | — | — | EP | disclosed |
| US-20200405866-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | HERON THERAPEUTICS, INC. | 2020-12-31 | — | — | US | disclosed |
| EP-3424492-B1 | SEMI-SOLID DELIVERY VECHICLE AND PHARMACEUTICAL COMPOSITIONS | HERON THERAPEUTICS INC (US) | 2020-05-27 | — | — | EP | disclosed |
| US-10357570-B2 | Methods of treating nausea utilizing semi-solid delivery vehicle compositions comprising granisetron | HERON THERAPEUTICS, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| EP-3424492-A1 | SEMI-SOLID DELIVERY VECHICLE AND PHARMACEUTICAL COMPOSITIONS | Heron Therapeutics, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |
| US-20180339052-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | HERCULES CAPITAL, INC., AS AGENT | 2018-11-29 | — | — | US | disclosed |
| EP-2902012-B1 | Semi-solid delivery vehicle and pharmaceutical compositions | HERON THERAPEUTICS INC (US) | 2018-08-08 | — | — | EP | disclosed |
| US-9913910-B2 | Methods of treating nausea utilizing semi-solid delivery vehicle compositions comprising granisetron | HERON THERAPEUTICS, INC. (US) | 2018-03-13 | — | — | US | disclosed |
| US-20170007705-A1 | SEMI-SOLID DELIVERY VEHICLE AND PHARMACEUTICAL COMPOSITIONS | HERCULES CAPITAL, INC., AS AGENT | 2017-01-12 | — | — | US | disclosed |
| US-6590059-B2 | Orthopedic implants or vehicles for sustained delivery of pharmaceutical, cosmetic and agricultural agents | AP PHARMA, INC. | 2003-07-08 | — | — | US | disclosed |
| EP-1280558-A2 | SEMI-SOLID DELIVERY VEHICLE AND PHARMACEUTICAL COMPOSITIONS | Advanced Polymer Systems, Inc. (US) | 2003-02-05 | — | — | EP | disclosed |
| US-20020176844-A1 | Bioerodible polyorthoesters containing hydrogen bonding groups | AP PHARMA, INC. | 2002-11-28 | — | — | US | disclosed |
| WO-2002092061-A1 | BIORODIBLE POLY(ORTHOESTERS) FROM DIOXOLANE-BASED DIKETENE ACETALS | A.P. PHARMA, INC. (US) | 2002-11-21 | — | — | WO | disclosed |
| WO-2002092661-A1 | PEG-POE, PEG-POE-PEG, AND POE-PEG-POE BLOCK COPOLYMERS | AP PHARMA, INC. (US) | 2002-11-21 | — | — | WO | disclosed |
| WO-2002092655-A1 | BIOERODIBLE POLY(ORTHOESTERS) CONTAINING HYDROGEN BONDING GROUPS | A.P. PHARMA, INC. (US) | 2002-11-21 | — | — | WO | disclosed |
| US-20020168336-A1 | Bioerodible polyorthoesters from dioxolane-based diketene acetals | HERON THERAPEUTICS, INC. (F/K/A A.P. PHARMA, INC.) | 2002-11-14 | — | — | US | disclosed |
| US-20020037300-A1 | Semi-solid delivery vehicle and pharmaceutical compositions | HERON THERAPEUTICS, INC. (F/K/A A.P. PHARMA, INC.) | 2002-03-28 | — | — | US | disclosed |
| WO-2001085139-A2 | SEMI-SOLID DELIVERY VEHICLE AND PHARMACEUTICAL COMPOSITIONS | ADVANCED POLYMER SYSTEMS, INC. (US) | 2001-11-15 | — | — | WO | disclosed |
| US-4549010-A | Bioerodible poly(ortho ester) thermoplastic elastomer from diketene diacetal | MERCK & CO., INC. (US) | 1985-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037300-A1 | Semi-solid delivery vehicle and pharmaceutical compositions | LIPA, CEL, SORD | CA12 1616/4885CA1 3455/4885CA2 2135/4885 |
| US-20200405866-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | LPXN, CRH, NTSR1 | CA12 951/4885CA1 883/4885CA2 1310/4885 |
| US-20020176844-A1 | Bioerodible polyorthoesters containing hydrogen bonding groups | PLOD3, HAO2, CD44 | CA12 1207/4885CA1 1022/4885CA2 1957/4885 |
| US-20210252156-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | LPXN, CRH, NTSR1 | CA12 951/4885CA1 883/4885CA2 1310/4885 |
| US-10357570-B2 | Methods of treating nausea utilizing semi-solid delivery vehicle compositions comprising granisetron | LPXN, CRH, NTSR1 | CA12 951/4885CA1 883/4885CA2 1310/4885 |
| US-20180339052-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | LPXN, CRH, NTSR1 | CA12 951/4885CA1 883/4885CA2 1310/4885 |
| US-20170007705-A1 | SEMI-SOLID DELIVERY VEHICLE AND PHARMACEUTICAL COMPOSITIONS | LIPA, CEL, SORD | CA12 1616/4885CA1 3455/4885CA2 2135/4885 |
| US-20020168336-A1 | Bioerodible polyorthoesters from dioxolane-based diketene acetals | HAAO, HAO2, HAO1 | CA12 1319/4885CA1 1206/4885CA2 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.