Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | EGFR | P00533 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.51 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462922 | 0.84 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL1462758 | 0.83 | MEN1 (0.59) | ALDH1A1SMN1; SMN2TSHREGFRMEN1 | |
| SCHEMBL6314890 | 0.80 | EGFR (0.86) | ALDH1A1SMN1; SMN2EGFRGAACASR | |
| SCHEMBL6314802 | 0.78 | EGFR (0.83) | ALDH1A1SMN1; SMN2EGFRCASR | |
| SCHEMBL13602214 | 0.76 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL1464587 | 0.75 | EGFR (0.67) | ALDH1A1SMN1; SMN2EGFRMEN1KMT2A | |
| SCHEMBL1463678 | 0.74 | MEN1 (0.59) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL13602184 | 0.74 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8011144 | 0.73 | LMNA (0.71) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL6307813 | 0.72 | EGFR (0.73) | ALDH1A1SMN1; SMN2EGFRCASRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-03-24 | — | — | US | claimed |
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-03-24 | — | — | US | disclosed |
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-03-24 | — | — | US | disclosed |
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-03-24 | — | — | US | disclosed |
| EP-2266962-A1 | THE COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences (CN) | 2010-12-29 | — | — | EP | disclosed |
| EP-2266962-A1 | THE COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences (CN) | 2010-12-29 | — | — | EP | disclosed |
| CN-101531638-A | Compounds useful as estrogen-related receptor modulators and uses thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | ESRRA, ESRRB, ESRRG | ALDH1A1 412/4885SMN1; SMN2 4538/4885TSHR 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.