Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010827 | 0.73 | SLC6A3 (0.42) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7244695 | 0.68 | — | — | |
| SCHEMBL10779350 | 0.68 | BRD4 (0.39) | BRD4SLC6A3GAA | |
| SCHEMBL19736432 | 0.66 | BRD4 (0.39) | BRD4GAA | |
| SCHEMBL14468370 | 0.66 | BRD4 (0.39) | BRD4GAA | |
| SCHEMBL29030969 | 0.65 | ATM (0.44) | BRD4SLC6A4SLC6A3SLC6A2GAA | |
| SCHEMBL10641800 | 0.65 | SMN1; SMN2 (0.41) | BRD4GAA | |
| SCHEMBL2477633 | 0.65 | AKR1C4 (0.51) | BRD4GAA | |
| SCHEMBL11514658 | 0.65 | AKR1C4 (0.48) | BRD4GAA | |
| SCHEMBL2477632 | 0.65 | AKR1C4 (0.51) | BRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070009432-A1 | Boat tropanes | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070009432-A1 | Boat tropanes | SLC6A3, SLC18A2, SLC6A4 | BRD4 1768/4885SLC6A4 3/4885SLC6A3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.