Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 4/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14468370 | 1.00 | BRD4 (0.39) | BRD4TLR4AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL10053671 | 0.80 | AKR1C4 (0.33) | AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL14035897 | 0.79 | AKR1C4 (0.53) | TLR4AKR1C4AKR1C3AKR1C2TSHR | |
| SCHEMBL22804147 | 0.79 | AKR1C4 (0.53) | TLR4AKR1C4AKR1C3AKR1C2TSHR | |
| SCHEMBL21121156 | 0.79 | CYP1A2 (0.38) | BRD4TLR4AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2477632 | 0.77 | AKR1C4 (0.51) | BRD4AKR1C4AKR1C3AKR1C2GAA | |
| SCHEMBL11514658 | 0.77 | AKR1C4 (0.48) | BRD4TLR4AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2477633 | 0.77 | AKR1C4 (0.51) | BRD4AKR1C4AKR1C3AKR1C2GAA | |
| SCHEMBL10053664 | 0.76 | AKR1C4 (0.40) | TLR4AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL4399643 | 0.76 | AKR1C4 (0.38) | BRD4AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362155-A1 | CIRCULAR ECONOMY METHODS OF PREPARING UNSATURATED COMPOUNDS | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362155-A1 | CIRCULAR ECONOMY METHODS OF PREPARING UNSATURATED COMPOUNDS | FADS1, SCD, FASN | BRD4 711/4885TLR4 4555/4885AKR1C4 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.