Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965372 | 0.89 | GAA (0.55) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL642298 | 0.89 | GAA (0.54) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL9965416 | 0.87 | GAA (0.57) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL9965373 | 0.86 | EPHX2 (0.52) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL9965380 | 0.83 | GAA (0.55) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL9965370 | 0.83 | ACHE (0.66) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL9965384 | 0.83 | GAA (0.54) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL9965371 | 0.81 | EPHX2 (0.55) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL641560 | 0.79 | GAA (0.54) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL640944 | 0.79 | GAA (0.62) | GAAPKMKMT2ARXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |