SCHEMBL642298

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL641560	0.90	GAA (0.54)	GAAPKMPTPN2PTPN1PTPN6
	SCHEMBL9965416	0.89	GAA (0.57)	GAAPKMKMT2AACHEBACE1
	SCHEMBL14639655	0.89	GAA (0.52)	GAAPKMKMT2AACHEBACE1
	SCHEMBL641226	0.88	STS (0.56)	GAAPKMPTPN2PTPN1PTPN6
	SCHEMBL9965372	0.87	GAA (0.55)	GAAPKMKMT2AACHEBACE1
	SCHEMBL9965380	0.85	GAA (0.55)	GAAPKMPTPN1KMT2AACHE
	SCHEMBL9965370	0.85	ACHE (0.66)	GAAPKMPTPN2PTPN1KMT2A
	SCHEMBL9965384	0.84	GAA (0.54)	GAAPKMPTPN1KMT2AACHE
	SCHEMBL9965373	0.84	EPHX2 (0.52)	GAAPKMPTPN1KMT2AACHE
	SCHEMBL641308	0.83	STS (0.55)	GAAPKMPTPN2PTPN1PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.