Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14454145 | 0.84 | BRD4 (0.31) | BRD4 | |
| SCHEMBL11926946 | 0.77 | NOTUM (0.35) | PARP1NOTUM | |
| SCHEMBL4344995 | 0.77 | PARP1 (0.46) | PARP1NOTUMBRD4 | |
| SCHEMBL27628450 | 0.74 | CGAS (0.38) | CDK2CDK9 | |
| SCHEMBL27404398 | 0.74 | MEN1 (0.38) | — | |
| SCHEMBL30748852 | 0.74 | PARP1 (0.33) | PARP1NOTUM | |
| SCHEMBL14959156 | 0.74 | AKT1 (0.39) | PARP1NOTUM | |
| SCHEMBL15635817 | 0.74 | PARP1 (0.33) | PARP1NOTUM | |
| SCHEMBL13861855 | 0.73 | BRD4 (0.31) | PARP1CDK2CDK9NOTUMBRD4 | |
| SCHEMBL14268235 | 0.73 | PARP1 (0.31) | PARP1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169785-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-01-30 | — | — | US | disclosed |