Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965428 | 0.94 | GAA (0.53) | GAAPKMTRPV1KMT2AACHE | |
| SCHEMBL14639656 | 0.88 | PTPN1 (0.49) | GAAPKMTRPV1KMT2AACHE | |
| SCHEMBL9965408 | 0.87 | GAA (0.49) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL642196 | 0.83 | GAA (0.56) | GAAPKMKMT2AACHEBACE1 | |
| SCHEMBL9965439 | 0.83 | KMT2A (0.53) | GAAPKMTRPV1KMT2AACHE | |
| SCHEMBL10173900 | 0.82 | PTPN1 (0.53) | GAAPKMTRPV1KMT2AACHE | |
| SCHEMBL9965426 | 0.81 | GAA (0.56) | GAAPKMTRPV1KMT2AACHE | |
| SCHEMBL9965406 | 0.80 | TRPV1 (0.51) | GAATRPV1KMT2APOLBL3MBTL1 | |
| SCHEMBL9965372 | 0.80 | GAA (0.55) | GAAPKMTRPV1KMT2AACHE | |
| SCHEMBL641308 | 0.80 | STS (0.55) | GAAPKMKMT2AACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |