Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14639698 | 0.88 | TDP1 (0.46) | TRPV1TP53GAAMAPTPOLB | |
| SCHEMBL9965458 | 0.84 | TP53 (0.49) | TRPV1TP53GAAMAPTPOLB | |
| SCHEMBL14639717 | 0.80 | GAA (0.49) | TRPV1TP53GAAMAPTPOLB | |
| SCHEMBL9965428 | 0.75 | GAA (0.53) | TRPV1TP53GAAMAPTPOLB | |
| SCHEMBL9965439 | 0.72 | KMT2A (0.53) | TRPV1TP53GAAMAPTPOLB | |
| SCHEMBL14639656 | 0.70 | PTPN1 (0.49) | TRPV1GAAPOLBF10LMNA | |
| SCHEMBL28218333 | 0.70 | TRPV1 (0.65) | TRPV1GAAMAPTTDP1KMT2A | |
| SCHEMBL9965381 | 0.70 | POLB (0.53) | TRPV1MAPTPOLBTDP1EPHX2 | |
| SCHEMBL14639571 | 0.67 | TSHR (0.42) | MAPTTSHRL3MBTL1KMT2A | |
| SCHEMBL9965408 | 0.67 | GAA (0.49) | GAAPOLBTDP1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960347-B1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | STERIX LTD (GB) | 2012-06-20 | — | — | EP | disclosed |