SCHEMBL14640209

SCHEMBL14640209

CCN(C(=O)C(F)(F)F)[C@@H](C)Cc1ccc(C(=O)CCC(=O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.48
USP5 P45974 1/20 0.46
KMT2A Q03164 1/20 0.42
NR4A2 P43354 1/20 0.39
CYP1A2 P05177 2/20 0.38
FFAR1 O14842 1/20 0.38
LMNA P02545 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
ALDH1A1 P00352 2/20 0.36
CYP2C19 P33261 2/20 0.36
GAA P10253 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
MMP2 P08253 2/20 0.35
MMP12 P39900 2/20 0.35
THRA P10827 2/20 0.35
THRB P10828 2/20 0.35
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14640208 0.84 HSD17B10 (0.43) FFAR1LMNASMN1; SMN2HIF1AALDH1A1
SCHEMBL14640210 0.82 CPA1 (0.44) KMT2ACYP1A2RAB9ACYP2C19SIGMAR1
SCHEMBL14640340 0.74 HDAC3 (0.45) L3MBTL1KMT2ALMNASMN1; SMN2ALDH1A1
SCHEMBL11239470 0.74 USP5 (0.53) L3MBTL1USP5KMT2ANR4A2CYP1A2
SCHEMBL3526490 0.74 USP5 (0.64) L3MBTL1USP5KMT2ANR4A2CYP1A2
SCHEMBL4062138 0.72 HTT (0.32) KMT2ALMNAALDH1A1HPGDHSD17B10
SCHEMBL25146524 0.70 LMNA (0.62) L3MBTL1USP5KMT2ANR4A2CYP1A2
SCHEMBL25263232 0.70 TAAR1 (0.49) SMN1; SMN2ALDH1A1GAAHPGD
SCHEMBL25313936 0.70 TAAR1 (0.49) SMN1; SMN2ALDH1A1GAAHPGD
SCHEMBL5081078 0.69 L3MBTL1 (0.73) L3MBTL1USP5KMT2ANR4A2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169907-B2 Derivatives, immunogens, and antibodies for detecting ecstasy-class drugs ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2007-01-30 US disclosed