SCHEMBL14640735

SCHEMBL14640735

Cc1ccc(S(=O)(=O)OCC(F)(F)C(F)C(F)(F)F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGER Q15109 1/20 0.38
STAT3 P40763 2/20 0.37
CA1 P00915 3/20 0.36
CA12 O43570 2/20 0.36
CA9 Q16790 2/20 0.36
GAA P10253 2/20 0.36
KMT2A Q03164 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
BCHE P06276 2/20 0.35
ACHE P22303 2/20 0.35
ALDH1A1 P00352 4/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
MEN1 O00255 2/20 0.35
VDR P11473 1/20 0.35
CA2 P00918 2/20 0.34
CA3 P07451 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL743574 0.88 GAA (0.44) AGERSTAT3CA1CA12CA9
SCHEMBL19436459 0.80 GAA (0.43) STAT3CA1CA12CA9GAA
SCHEMBL1980138 0.80 GAA (0.43) STAT3CA1CA12CA9GAA
SCHEMBL68796 0.80 GAA (0.43) STAT3CA1CA12CA9GAA
SCHEMBL1742195 0.80 GAA (0.46) STAT3CA1CA12CA9GAA
SCHEMBL28300633 0.79 GAA (0.42) STAT3CA1CA12CA9GAA
SCHEMBL28998782 0.79 ALDH1A1 (0.43) STAT3CA1CA12CA9GAA
SCHEMBL979617 0.79 ALDH1A1 (0.43) STAT3CA1CA12CA9GAA
SCHEMBL2057211 0.79 ALDH1A1 (0.46) STAT3CA1CA12CA9GAA
SCHEMBL2533175 0.78 GAA (0.41) STAT3CA1CA12CA9GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746079-A2 Fluorinated biphenyl compounds for use in liquid crystal compositions Merck Patent GmbH (DE) 2007-01-24 EP disclosed