Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640735 | 0.88 | AGER (0.38) | GAAPOLBMEN1KMT2ANPSR1 | |
| SCHEMBL68796 | 0.83 | GAA (0.43) | GAAMEN1KMT2AALDH1A1STAT3 | |
| SCHEMBL1980138 | 0.83 | GAA (0.43) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19436459 | 0.83 | GAA (0.43) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30417836 | 0.82 | CYP2C19 (0.39) | GAAPOLBMEN1KMT2ANPSR1 | |
| SCHEMBL28300633 | 0.81 | GAA (0.42) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28998782 | 0.81 | ALDH1A1 (0.43) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL979617 | 0.81 | ALDH1A1 (0.43) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2533175 | 0.80 | GAA (0.41) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30775482 | 0.80 | USP2 (0.42) | GAAPOLBMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236589-A1 | THERAPEUTIC PHENETHYLAMINE COMPOSITIONS AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2025-07-24 | — | — | US | disclosed |
| US-11760737-B2 | Process for manufacturing 4-(2,2,3,3-tetrafluoropropyl)morpholine | ADVERIO PHARM GmbH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11760737-B2 | Process for manufacturing 4-(2,2,3,3-tetrafluoropropyl)morpholine | ADVERIO PHARM GmbH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11760737-B2 | Process for manufacturing 4-(2,2,3,3-tetrafluoropropyl)morpholine | ADVERIO PHARM GmbH (DE) | 2023-09-19 | — | — | US | disclosed |
| WO-2023156450-A1 | THERAPEUTIC PHENETHYLAMINE COMPOSITIONS AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2023-08-24 | — | — | WO | disclosed |
| CN-115697978-A | Method for preparing methyl {4,6-diamino-2- [ 5-fluoro-1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b ] pyridin-3-yl ] pyrimidin-5-yl } carbamate | 阿德弗里奥药品有限责任公司 | 2023-02-03 | — | — | CN | disclosed |
| US-20220332718-A1 | PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | GENENTECH, INC. (US) | 2022-10-20 | — | — | US | disclosed |
| US-20220089554-A1 | PROCESS FOR MANUFACTURING 4-(2,2,3,3-TETRAFLUOROPROPYL)MORPHOLINE | ADVERIO PHARMA GMBH (DE) | 2022-03-24 | — | — | US | disclosed |
| EP-3914588-A1 | PROCESS FOR MANUFACTURING 4-(2,2,3,3-TETRAFLUOROPROPYL)MORPHOLINE | Adverio Pharma GmbH (DE) | 2021-12-01 | — | — | EP | disclosed |
| CN-108473498-B | Pyrazolo [1,5a ] pyrimidine derivatives as IRAK4 modulators | 豪夫迈·罗氏有限公司 | 2021-11-02 | — | — | CN | disclosed |
| US-5106526-A | AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE, METHANOL AND A HYDROCARBON CONTAINING SIX CARBON ATOMS | ALLIED-SIGNAL INC. (US) | 1992-04-21 | — | — | US | disclosed |
| WO-1991018965-A1 | AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE, METHANOL AND A HYDROCARBON CONTAINING SIX CARBON ATOMS | ALLIED-SIGNAL INC. (US) | 1991-12-12 | — | — | WO | disclosed |
| WO-1991019019-A1 | AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE, METHANOL AND 1,2-DICHLOROETHYLENE | ALLIED-SIGNAL INC. (US) | 1991-12-12 | — | — | WO | disclosed |
| WO-1991005082-A1 | AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE AND 1,2-DICHLOROETHYLENE | ALLIED-SIGNAL INC. (US) | 1991-04-18 | — | — | WO | disclosed |
| WO-1990010096-A1 | A METHOD OF CLEANING USING HYDROCHLOROFLUOROCARBONS | ALLIED-SIGNAL INC. (US) | 1990-09-07 | — | — | WO | disclosed |
| US-4947881-A | Method of cleaning using hydrochlorofluorocarbons | ALLIED-SIGNAL INC. (US) | 1990-08-14 | — | — | US | disclosed |
| US-4808620-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIALLERGENS, ANTIARTHRITIC, ANTIRHEUMATIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0254241-A1 | Pyrazolopyridine compounds, their preparation and use | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-27 | — | — | EP | disclosed |
| EP-0155486-A1 | 1,3,5-Trisubstituted 1,2,4-triazole derivatives, process for their preparation and medicinal preparations containing them | ALKALOIDA VEGYéSZETI GYáR (HU) | 1985-09-25 | — | — | EP | disclosed |
| US-4535076-A | INSECTICIDES; MITICIDES, NEMATOCIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250236589-A1 | THERAPEUTIC PHENETHYLAMINE COMPOSITIONS AND METHODS OF USE | PNMT, HTR2C, HTR2A | GAA 2280/4885POLB 2707/4885MEN1 467/4885 |
| US-20220089554-A1 | PROCESS FOR MANUFACTURING 4-(2,2,3,3-TETRAFLUOROPROPYL)MORPHOLINE | CYP4F3, CYP4F2, TNNT2 | GAA 1319/4885POLB 3361/4885MEN1 656/4885 |
| US-20220332718-A1 | PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | IRAK1, IRAK4, IRAK2 | GAA 4340/4885POLB 2188/4885MEN1 3780/4885 |
| US-11760737-B2 | Process for manufacturing 4-(2,2,3,3-tetrafluoropropyl)morpholine | CYP4F3, CYP4F2, TNNT2 | GAA 1319/4885POLB 3361/4885MEN1 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.