SCHEMBL146412

SCHEMBL146412

O=C1C=CC(=O)N1Cc1ccc(CN2C(=O)C=CC2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 9/20 1.00
FAAH O00519 5/20 1.00
GSK3A P49840 5/20 0.77
GSK3B P49841 5/20 0.77
PTGS1 P23219 2/20 0.69
PTGS2 P35354 2/20 0.69
CMA1 P23946 2/20 0.48
F2 P00734 1/20 0.48
PLG P00747 1/20 0.48
ELANE P08246 1/20 0.48
CTSG P08311 1/20 0.48
CTRC Q99895 1/20 0.48
ALDH1A1 P00352 2/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
GMNN O75496 1/20 0.48
THPO P40225 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8950019 0.93 MGLL (0.86) MGLLFAAHGSK3AGSK3BPTGS1
SCHEMBL21215698 0.93 MGLL (0.86) MGLLFAAHGSK3AGSK3BPTGS1
SCHEMBL7218376 0.91 MGLL (0.82) MGLLFAAHGSK3AGSK3BPTGS1
SCHEMBL15657951 0.89 MGLL (0.78) MGLLFAAHGSK3AGSK3BPTGS1
SCHEMBL7871290 0.89 MGLL (0.78) MGLLFAAHGSK3AGSK3BPTGS1
SCHEMBL19555152 0.89 MGLL (0.78) MGLLFAAHGSK3AGSK3BPTGS1
SCHEMBL9610843 0.89 MGLL (1.00) MGLLFAAHGSK3AGSK3BPTGS1
SCHEMBL15704375 0.89 MGLL (0.78) MGLLFAAHGSK3AGSK3BPTGS1
SCHEMBL4804503 0.89 MGLL (0.78) MGLLFAAHGSK3AGSK3BPTGS1
SCHEMBL4800190 0.89 MGLL (0.78) MGLLFAAHGSK3AGSK3BPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 410 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119490747-A Resin composition, prepreg comprising same, laminated board and metal foil-clad laminated board 广东生益科技股份有限公司 2025-02-21 CN claimed
US-20240351981-A1 NOVEL BISMALEIMIDE COMPOUNDS HAVING IMPROVED SOLUBILITY AND THEIR USE IN CURABLE COMPOSITIONS EVONIK OPERATIONS GMBH (DE) 2024-10-24 US claimed
US-20240327681-A1 BONDING SYSTEM DDP SPECIALTY ELECTRONIC MATERIALS US LLC (US) 2024-10-03 US claimed
CN-118256088-A Resin composition and application thereof 广东生益科技股份有限公司 2024-06-28 CN claimed
CN-118240342-A Thermosetting resin composition and application thereof 广东生益科技股份有限公司 2024-06-25 CN claimed
EP-4380922-A1 NOVEL BISMALEIMIDE COMPOUNDS HAVING IMPROVED SOLUBILITY AND THEIR USE IN CURABLE COMPOSITIONS Evonik Operations GmbH (DE) 2024-06-12 EP claimed
CN-116496199-A Modified maleimide compound and application thereof 广东生益科技股份有限公司 2023-07-28 CN claimed
CN-116410595-A Resin composition, prepreg comprising same, and metal foil-clad laminate 广东生益科技股份有限公司 2023-07-11 CN claimed
CN-116410596-A Resin composition and application thereof 广东生益科技股份有限公司 2023-07-11 CN claimed
CN-116410594-A Resin composition, prepreg and metal foil-clad laminate 广东生益科技股份有限公司 2023-07-11 CN claimed
US-4806419-A HEAT RESISTANCE, IMPACT STRENGTH THE BOOTS COMPANY PLC (GB) 1989-02-21 US claimed
US-4789704-A BINDERS FOR COMPOSITES, FILMS, LAMINATES; HIGH FRACTURE TOUGHNESS TECHNOCHEMIE GMBH (DE) 1988-12-06 US claimed
EP-0165812-B1 THERMOSETTING IMIDE RESIN COMPOSITIONS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1988-11-09 EP claimed
US-4737568-A Curable resin from bis-imide amino acid hydrazide and alkenyl phenol or ether THE BOOTS COMPANY PLC (GB) 1988-04-12 US claimed
EP-0212808-A2 Curable resins Technochemie GmbH - Verfahrenstechnik (DE) 1987-03-04 EP claimed
EP-0131027-B1 CURABLE THERMOSETTING PREPOLYMERISED IMIDE RESIN COMPOSITIONS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1986-12-17 EP claimed
EP-0141612-A2 Curable Bisimide Resin Mixtures Technochemie GmbH - Verfahrenstechnik (DE) 1985-05-15 EP claimed
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4035345-A Thermosetting bis-imide compositions RHONE-POULENC S.A. (FR) 1977-07-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240351981-A1 NOVEL BISMALEIMIDE COMPOUNDS HAVING IMPROVED SOLUBILITY AND THEIR USE IN CURABLE COMPOSITIONS PBRM1, SMCHD1, SMARCE1 MGLL 3949/4885FAAH 1732/4885GSK3A 3136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.