Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | TACR2 | P21452 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.48 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14603133 | 0.89 | CASP3 (0.64) | CASP3CASP1ALDH1A1GAACTSL | |
| SCHEMBL5650545 | 0.89 | CASP3 (0.64) | CASP3CASP1ALDH1A1GAACTSL | |
| SCHEMBL14641301 | 0.89 | CASP3 (0.64) | CASP3CASP1ALDH1A1GAACTSL | |
| SCHEMBL14603128 | 0.86 | CASP3 (0.61) | CASP3CASP1ALDH1A1GAACTSL | |
| SCHEMBL14603132 | 0.86 | CASP3 (0.61) | CASP3CASP1ALDH1A1GAACTSL | |
| SCHEMBL14641489 | 0.86 | CASP3 (0.61) | CASP3CASP1ALDH1A1GAACTSL | |
| SCHEMBL6601810 | 0.86 | CASP3 (0.68) | CASP3TACR2CASP1 | |
| SCHEMBL28777681 | 0.85 | CASP3 (0.54) | CASP3TACR2SRCCASP1ALDH1A1 | |
| SCHEMBL13043811 | 0.84 | CASP3 (0.53) | CASP3CASP1ALDH1A1GAACTSL | |
| SCHEMBL14337553 | 0.84 | CASP3 (0.53) | CASP3CASP1ALDH1A1GAACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |
| EP-1165532-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058294-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |