Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784633 | 0.81 | CYP4F2 (0.54) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL14606148 | 0.81 | F3 (0.56) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL25376539 | 0.81 | CYP4F2 (0.50) | CYP4F2CYP4A11CYP4Z1ALDH1A1GAA | |
| SCHEMBL29438260 | 0.80 | THRB (0.57) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL25305917 | 0.80 | THRB (0.57) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10456252 | 0.80 | CYP4F2 (0.53) | CYP4F2CYP4A11CYP4Z1ALDH1A1GAA | |
| SCHEMBL10456253 | 0.80 | CYP4F2 (0.53) | CYP4F2CYP4A11CYP4Z1ALDH1A1GAA | |
| SCHEMBL4113212 | 0.80 | CYP4F2 (0.76) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL645184 | 0.79 | CYP4F2 (0.59) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL13908760 | 0.79 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169786-B2 | Isoxazoline derivatives as anti-depressants | JANSSEN-CILAG S.A. (ES) | 2007-01-30 | — | — | US | disclosed |