Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12107604 | 0.87 | ATAD2 (0.39) | ATAD2BRD4GRIN1GRIN2BHPGD | |
| SCHEMBL18055285 | 0.85 | ATAD2 (0.36) | ATAD2BRD4GRIN1GRIN2BHPGD | |
| SCHEMBL12333333 | 0.79 | ATAD2 (0.42) | ATAD2BRD4GRIN1GRIN2BHPGD | |
| SCHEMBL12110139 | 0.78 | ESR2 (0.44) | GRIN1GRIN2B | |
| SCHEMBL18421351 | 0.77 | ATAD2 (0.72) | ATAD2BRD4GRIN1GRIN2BBMPR1B | |
| SCHEMBL2061080 | 0.75 | ATAD2 (0.60) | ATAD2SMN1; SMN2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL2060542 | 0.75 | ATAD2 (0.47) | ATAD2BRD4SMN1; SMN2CYP1A2 | |
| SCHEMBL3629805 | 0.75 | HTT (0.50) | HPGDHTTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL12110391 | 0.74 | GRIN1 (0.34) | ATAD2BRD4GRIN1GRIN2BCHRM1 | |
| SCHEMBL12110145 | 0.74 | CHRM1 (0.35) | ATAD2BRD4GRIN1GRIN2BCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2546255-A1 | BENZAZEPINE COMPOUND | Astellas Pharma Inc. (JP) | 2013-01-16 | — | — | EP | disclosed |