Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.71 |
| ▸ | MMP10 | P09238 | 8/20 | 0.71 |
| ▸ | MMP8 | P22894 | 8/20 | 0.71 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934537 | 0.83 | MMP13 (1.00) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL4930333 | 0.75 | MMP13 (1.00) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL4934527 | 0.74 | MMP13 (0.82) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL4934974 | 0.73 | MMP13 (1.00) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL4932758 | 0.73 | MMP13 (1.00) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL8107876 | 0.73 | MMP13 (0.72) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL4933981 | 0.73 | MMP13 (0.80) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL4934618 | 0.73 | MMP13 (1.00) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL8109228 | 0.72 | MMP13 (0.72) | MMP13MMP10MMP8MMP2MMP3 | |
| SCHEMBL941436 | 0.72 | MMP13 (0.59) | MMP13MMP10MMP8MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740551-B9 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF AS AN MMP-13 INHIBITOR | TAKEDA PHARMACEUTICAL (JP) | 2013-01-16 | — | — | EP | disclosed |