Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15998535 | 0.83 | IDO1 (0.43) | APLNRKMT2AALDH1A1MEN1CA12 | |
| SCHEMBL11295684 | 0.83 | GPR84 (0.47) | APLNRKDM1AMAOAMAOBKMT2A | |
| SCHEMBL1690285 | 0.81 | HTT (0.46) | APLNRKDM1AMAOAMAOBKMT2A | |
| SCHEMBL5177898 | 0.80 | KMT2A (0.50) | APLNRKDM1AMAOAMAOBKMT2A | |
| SCHEMBL24411006 | 0.79 | CA12 (0.45) | APLNRKDM1AMAOAMAOBKMT2A | |
| SCHEMBL7704446 | 0.79 | KMT2A (0.46) | APLNRKDM1AMAOAMAOBKMT2A | |
| SCHEMBL3258877 | 0.79 | IDO1 (0.48) | APLNRKDM1AMAOAMAOBKMT2A | |
| SCHEMBL16139667 | 0.79 | APLNR (0.63) | APLNRALDH1A1CA12CA1CA2 | |
| SCHEMBL7826059 | 0.79 | CA12 (0.46) | APLNRKDM1AMAOAMAOBKMT2A | |
| SCHEMBL10696244 | 0.79 | APLNR (0.44) | APLNRKDM1AMAOAMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354432-B2 | Cyclic derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-15 | — | — | US | disclosed |