Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 14/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602863 | 0.83 | ACVRL1 (0.43) | PIK3CDACVRL1ADK | |
| SCHEMBL14642596 | 0.82 | PIK3CD (0.41) | PIK3CDACVRL1 | |
| SCHEMBL10101600 | 0.81 | ADK (0.41) | PIK3CDACVRL1ADK | |
| SCHEMBL10101531 | 0.81 | ADK (0.41) | PIK3CDACVRL1ADK | |
| SCHEMBL14642599 | 0.80 | ACVRL1 (0.37) | PIK3CDACVRL1 | |
| SCHEMBL14642816 | 0.80 | ACVRL1 (0.41) | PIK3CDACVRL1 | |
| SCHEMBL13519810 | 0.79 | PIK3CD (0.41) | PIK3CDACVRL1ADK | |
| SCHEMBL10101597 | 0.78 | ADK (0.45) | PIK3CDACVRL1ADK | |
| SCHEMBL13519756 | 0.78 | ACVRL1 (0.36) | PIK3CDACVRL1 | |
| SCHEMBL14642530 | 0.78 | ACVRL1 (0.36) | PIK3CDACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018013-A1 | BICYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018013-A1 | BICYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | NTPCR, PNP, DCTD | PIK3CD 636/4885ACVRL1 4215/4885ADK 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.