Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 4/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 14/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 13/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 12/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15962789 | 0.75 | PRMT5 (0.38) | ADKPRMT5WDR77METTL3LCK | |
| SCHEMBL16982320 | 0.74 | ADK (0.70) | ADK | |
| SCHEMBL16968477 | 0.74 | ADK (0.70) | ADK | |
| SCHEMBL18744586 | 0.74 | ADK (0.70) | ADK | |
| SCHEMBL18744584 | 0.74 | ADK (0.70) | ADK | |
| SCHEMBL14644673 | 0.73 | PRMT5 (0.50) | ADKPRMT5WDR77METTL3 | |
| SCHEMBL14644659 | 0.73 | PRMT5 (0.50) | ADKPRMT5WDR77METTL3 | |
| SCHEMBL13173244 | 0.72 | AHCY (0.54) | — | |
| SCHEMBL13173231 | 0.72 | AHCY (0.54) | — | |
| SCHEMBL14643246 | 0.71 | KDR (0.56) | LCKSRCKDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013009735-A1 | 5'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2013-01-17 | — | — | WO | disclosed |