Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14644658 | 0.87 | ADK (0.41) | ADKPRMT5WDR77 | |
| SCHEMBL14544365 | 0.84 | PRMT5 (0.52) | ADKPRMT5WDR77METTL3METTL14 | |
| SCHEMBL22434980 | 0.81 | ADK (0.52) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL22434979 | 0.81 | ADK (0.52) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL14544374 | 0.81 | ADK (0.44) | ADKABL1RIN1PRMT5WDR77 | |
| SCHEMBL23023836 | 0.81 | ADK (0.72) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL24687181 | 0.81 | ADK (0.72) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL31123791 | 0.81 | ADK (0.72) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL14644664 | 0.81 | ADK (0.41) | ADKABL1RIN1PRMT5WDR77 | |
| SCHEMBL14644369 | 0.80 | ADK (0.41) | ADKABL1RIN1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013009735-A1 | 5'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2013-01-17 | — | — | WO | disclosed |