Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29142204 | 0.84 | CYP3A4 (0.39) | CYP3A4CYP2D6CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL11490823 | 0.84 | FKBP1A (0.49) | CYP3A4CYP2D6FKBP1A | |
| SCHEMBL11490824 | 0.84 | FKBP1A (0.49) | CYP3A4CYP2D6FKBP1A | |
| SCHEMBL13601738 | 0.84 | FKBP1A (0.49) | CYP3A4CYP2D6FKBP1A | |
| SCHEMBL26694471 | 0.83 | FKBP1A (0.37) | CYP3A4CYP2D6CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL7262161 | 0.82 | FKBP1A (0.46) | FKBP1A | |
| Hydrochloric Acid SCHEMBL28782114 | 0.82 | CYP3A4 (0.38) | CYP3A4CYP2D6CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL14645016 | 0.81 | FKBP1A (0.41) | FKBP1A | |
| SCHEMBL6256971 | 0.81 | CYP3A4 (0.41) | CYP3A4CYP2D6CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL12660873 | 0.81 | CYP3A4 (0.37) | CYP3A4CYP2D6CHRNB2CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357654-B2 | Multimeric CD40 ligands, method for preparing same and use thereof for preparing drugs | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-22 | — | — | US | disclosed |