Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2275226 | 0.83 | POLB (0.49) | CYP3A4CYP2D6POLBSMN1; SMN2 | |
| SCHEMBL3568144 | 0.83 | POLB (0.49) | CYP3A4CYP2D6POLBSMN1; SMN2 | |
| SCHEMBL2651732 | 0.83 | POLB (0.49) | CYP3A4CYP2D6POLBSMN1; SMN2 | |
| SCHEMBL15146808 | 0.82 | CYP2D6 (0.39) | CYP3A4CYP2D6POLBSMN1; SMN2 | |
| SCHEMBL27363236 | 0.82 | CYP3A4 (0.46) | CYP3A4CYP2D6POLBL3MBTL3ACE | |
| SCHEMBL21211585 | 0.82 | CYP3A4 (0.41) | CYP3A4CYP2D6POLBCHRNB2CHRNA7 | |
| SCHEMBL11100722 | 0.82 | CYP3A4 (0.41) | CYP3A4CYP2D6POLBCHRNB2CHRNA7 | |
| SCHEMBL14645015 | 0.81 | CYP3A4 (0.38) | CYP3A4CYP2D6CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL24569258 | 0.79 | CYP3A4 (0.39) | CYP3A4CYP2D6POLBCHRNB2CHRNA7 | |
| SCHEMBL11490823 | 0.79 | FKBP1A (0.49) | CYP3A4CYP2D6POLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005065675-A1 | METHOD OF TREATMENT | PREMACS INTERNATIONAL PTY. LTD. (AU) | 2005-07-21 | — | — | WO | disclosed |