Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952204 | 0.81 | TSHR (0.50) | KMT2AMEN1KDM4EPOLBNPC1 | |
| SCHEMBL3788448 | 0.79 | PTK2 (0.38) | KMT2AMEN1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL3961199 | 0.76 | MEN1 (0.44) | KMT2AMEN1KDM4EPOLBTDP1 | |
| SCHEMBL70575 | 0.75 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL31613086 | 0.75 | MEN1 (0.43) | KMT2AMEN1KDM4EPOLBTDP1 | |
| SCHEMBL163274 | 0.75 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL171052 | 0.75 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL190088 | 0.73 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL19439589 | 0.73 | KMT2A (0.51) | KMT2AMEN1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL15111367 | 0.73 | KMT2A (0.51) | KMT2AMEN1SMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817304-A1 | NOVEL COMPOUNDS AND THEIR USE IN THERAPY | BioChromix NewCo AB (SE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013009259-A1 | NOVEL COMPOUNDS AND THEIR USE IN THERAPY | BIOCHROMIX PHARMA AB (SE) | 2013-01-17 | — | — | WO | disclosed |