SCHEMBL70575

SCHEMBL70575

COC(=O)c1ccsc1C(=O)OC

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.56
NPC1 O15118 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.53
MEN1 O00255 2/20 0.53
CYP1A2 P05177 1/20 0.53
HPGD P15428 3/20 0.51
KDM4E B2RXH2 5/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
NPSR1 Q6W5P4 2/20 0.49
ALDH1A1 P00352 2/20 0.49
MAPK10 P53779 2/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
POLB P06746 2/20 0.47
PKM P14618 1/20 0.47
ATM Q13315 1/20 0.47
MAPK1 P28482 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2654173 0.88 KMT2A (0.54) KMT2ANPC1SMN1; SMN2MEN1CYP1A2
SCHEMBL1974763 0.88 KDM4E (0.51) KMT2ANPC1SMN1; SMN2MEN1CYP1A2
SCHEMBL17873718 0.88 KMT2A (0.50) KMT2ANPC1SMN1; SMN2MEN1CYP1A2
SCHEMBL1973549 0.88 KDM4E (0.57) KMT2ANPC1SMN1; SMN2MEN1CYP1A2
SCHEMBL25304281 0.86 KMT2A (0.51) KMT2ANPC1SMN1; SMN2MEN1CYP1A2
SCHEMBL3977005 0.86 ALDH1A1 (0.55) KMT2ANPC1SMN1; SMN2MEN1CYP1A2
SCHEMBL28412622 0.85 KMT2A (0.50) KMT2ANPC1SMN1; SMN2MEN1CYP1A2
SCHEMBL25261430 0.83 HPGD (0.49) KMT2ANPC1SMN1; SMN2MEN1CYP1A2
SCHEMBL157777 0.83 HPGD (0.70) KMT2ANPC1SMN1; SMN2MEN1CYP1A2
SCHEMBL3579523 0.80 NPC1 (0.65) KMT2ANPC1SMN1; SMN2MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178389-A Preparation method of linagoli 浙江科聚生物医药有限公司 2023-05-30 CN claimed
CN-115572375-A High-heat-resistance and high-transparency copolyester resin and preparation method thereof 浙江大学 2023-01-06 CN claimed
CN-115044026-A Degradable high-barrier uvioresistant bio-based polyester and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-09-13 CN claimed
CN-112592471-B High-heat-resistance high-toughness polyester, polyester product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2021-05-07 CN claimed
CN-112592471-A High-heat-resistance high-toughness polyester, polyester product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2021-04-02 CN claimed
CN-119119436-A High-transparency light-color heat-resistant copolyester and preparation method thereof 万华化学集团股份有限公司 2024-12-13 CN disclosed
CN-115232144-B Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof 长春金赛药业有限责任公司 2024-04-02 CN disclosed
CN-116178389-A Preparation method of linagoli 浙江科聚生物医药有限公司 2023-05-30 CN disclosed
CN-115572375-A High-heat-resistance and high-transparency copolyester resin and preparation method thereof 浙江大学 2023-01-06 CN disclosed
CN-115232144-A Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof 长春金赛药业有限责任公司 2022-10-25 CN disclosed
CN-115044026-A Degradable high-barrier uvioresistant bio-based polyester and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-09-13 CN disclosed
CN-114940748-A High-heat-resistance high-barrier anti-ultraviolet bio-based copolyester and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-08-26 CN disclosed
US-5111327-A Substituted 3,4-polymethylenedioxythiophenes, and polymers and electro responsive devices made therefrom GENERAL ELECTRIC COMPANY (US) 1992-05-05 US disclosed
EP-0267794-A2 Process for preparing polyolefins Nippon Petrochemicals Co., Ltd. (JP) 1988-05-18 EP disclosed
EP-0052471-B1 PROCESS AND CATALYST FOR POLYMERIZATION OF OLEFINS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-09-18 EP disclosed
US-4526941-A Contacting alpha olefin with catalyst comprising organomagnesium compound, titanium compound, nitrogen or sulfur heterocyclic compound, slurry component and organometallic component ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-07-02 US disclosed
US-4525555-A TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS NIPPON OIL COMPANY, LIMITED (JP) 1985-06-25 US disclosed
EP-0052471-A1 Process and catalyst for polymerization of olefins Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-05-26 EP disclosed
US-4330650-A HAVING MAGNESIUM COMPONENTS, TITANIUM COMPONENTS, ORGANOALUMINUM COMPONENTS AND HETEROCYCLIC CARBOXYLIC ESTER ELECTRON DONOR COMPONENTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-05-18 US disclosed
US-4255280-A ORGANOMAGNESIUM, CHLOROSILANE, TITANIUM, ORGANOMETALLIC AND HETEROCYCLIC ESTER COMPONENTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-03-10 US disclosed