Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA7 | P43166 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645263 | 0.81 | KMT2A (0.49) | TSHRHSD17B10ALDH1A1KDM4EPOLB | |
| SCHEMBL1844052 | 0.79 | TSHR (0.57) | TSHRHSD17B10ALDH1A1CA12CA1 | |
| SCHEMBL5078857 | 0.77 | TSHR (0.55) | TSHRHSD17B10ALDH1A1CA12CA1 | |
| SCHEMBL162212 | 0.77 | TSHR (0.55) | TSHRHSD17B10ALDH1A1CA12CA1 | |
| SCHEMBL28618971 | 0.76 | TSHR (0.53) | TSHRHSD17B10ALDH1A1CA12CA1 | |
| SCHEMBL6034348 | 0.76 | TSHR (0.53) | TSHRHSD17B10ALDH1A1CA12CA1 | |
| SCHEMBL28358271 | 0.76 | TSHR (0.53) | TSHRHSD17B10ALDH1A1CA12CA1 | |
| SCHEMBL1513079 | 0.76 | TSHR (0.53) | TSHRHSD17B10ALDH1A1CA12CA1 | |
| SCHEMBL225275 | 0.76 | ALDH1A1 (0.54) | TSHRHSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL5240541 | 0.75 | TSHR (0.52) | TSHRHSD17B10ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |