Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 20/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL10557547 | 0.90 | HDAC4 (0.64) | HDAC4HDAC6HDAC8 | |
| SCHEMBL22530124 | 0.89 | HDAC4 (0.59) | HDAC4HDAC6HDAC8 | |
| SCHEMBL29757323 | 0.89 | HDAC4 (0.56) | HDAC4HDAC6HDAC8 | |
| SCHEMBL27957379 | 0.89 | HDAC4 (0.71) | HDAC4HDAC6HDAC8 | |
| SCHEMBL20049299 | 0.88 | HDAC4 (0.66) | HDAC4HDAC6HDAC8 | |
| SCHEMBL19071237 | 0.87 | HDAC6 (0.72) | HDAC4HDAC6HDAC8 | |
| SCHEMBL21189927 | 0.86 | HDAC4 (0.70) | HDAC4HDAC6HDAC8 | |
| SCHEMBL18824381 | 0.86 | HDAC4 (0.66) | HDAC4HDAC6HDAC8 | |
| SCHEMBL18824437 | 0.86 | HDAC4 (0.68) | HDAC4HDAC6HDAC8 | |
| SCHEMBL19100119 | 0.86 | HDAC4 (0.72) | HDAC4HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751373-A | Benzoic acid thioester compound containing trifluoromethyl oxadiazole fragment, and preparation method and application thereof | 沈阳农业大学 | 2025-04-04 | — | — | CN | claimed |
| US-20250107533-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-03 | — | — | US | claimed |
| EP-4432834-A1 | FUNGICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2024-09-25 | — | — | EP | claimed |
| CN-118265452-A | Fungicidal compositions | 先正达农作物保护股份公司 | 2024-06-28 | — | — | CN | claimed |
| CN-113788800-B | Preparation method and application of 5-trifluoromethyl substituted oxadiazole compound containing diphenyl ether group | 南京林业大学 | 2023-09-26 | — | — | CN | claimed |
| WO-2023089007-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-25 | — | — | WO | claimed |
| CN-113788800-A | Preparation method and application of diphenyl ether group-containing 5-trifluoromethyl substituted oxadiazole compound | 南京林业大学 | 2021-12-14 | — | — | CN | claimed |
| US-12583828-B2 | Preparation of aromatic carbonyl compounds by catalytic oxidation with molecular oxygen | BASF SE (DE) | 2026-03-24 | — | — | US | disclosed |
| CN-119751373-A | Benzoic acid thioester compound containing trifluoromethyl oxadiazole fragment, and preparation method and application thereof | 沈阳农业大学 | 2025-04-04 | — | — | CN | disclosed |
| US-20250107533-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-03 | — | — | US | disclosed |
| CN-119707854-A | Preparation and application of N- (substituted phenyl) carbamoyl-4- (5- (trifluoromethyl) -1,2, 4-oxadiazole-3-yl) aryl formamide | 河北大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119591556-A | N, N-disubstituted-4- (5- (trifluoromethyl) -1,2, 4-oxadiazole-3-yl) benzamide compound and preparation and application thereof | 河北大学 | 2025-03-11 | — | — | CN | disclosed |
| CN-119591595-A | HDAC6 inhibitor, pharmaceutical composition and application | 四川大学华西医院 | 2025-03-11 | — | — | CN | disclosed |
| EP-2729454-B1 | NOVEL TRIFLUOROMETHYL-OXADIAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2015-09-16 | — | — | EP | disclosed |
| US-9056843-B2 | Trifluoromethyl-oxadiazole derivatives and their use in the treatment of disease | NOVARTIS AG (CH) | 2015-06-16 | — | — | US | disclosed |
| US-20140329825-A1 | NOVEL TRIFLUOROMETHYL-OXADIAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2014-11-06 | — | — | US | disclosed |
| US-20140142105-A1 | NOVEL TRIFLUOROMETHYL-OXADIAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2014-05-22 | — | — | US | disclosed |
| EP-2729454-A1 | NOVEL TRIFLUOROMETHYL-OXADIAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | Novartis AG (CH) | 2014-05-14 | — | — | EP | disclosed |
| CN-103764635-A | Novel trifluoromethyl-oxadiazole derivatives and their use in the treatment of disease | NOVARTIS AG | 2014-04-30 | — | — | CN | disclosed |
| WO-2013008162-A1 | NOVEL TRIFLUOROMETHYL-OXADIAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2013-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142105-A1 | NOVEL TRIFLUOROMETHYL-OXADIAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | HDAC4, HDAC5, HDAC6 | HDAC4 1/4885HDAC6 3/4885HDAC8 9/4885 |
| US-12583828-B2 | Preparation of aromatic carbonyl compounds by catalytic oxidation with molecular oxygen | AOC2, NOX1, AOC3 | HDAC4 3294/4885HDAC6 2922/4885HDAC8 4281/4885 |
| US-20250107533-A1 | FUNGICIDAL COMPOSITIONS | CYP51A1, AAAS, PIK3C3 | HDAC4 206/4885HDAC6 129/4885HDAC8 440/4885 |
| US-20140329825-A1 | NOVEL TRIFLUOROMETHYL-OXADIAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | HDAC4, HDAC5, HDAC6 | HDAC4 1/4885HDAC6 3/4885HDAC8 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.