Benzene

Benzene

SCHEMBL14645900

C=CCBr.c1ccccc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.75
ALDH1A1 P00352 4/20 0.33
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887973 0.87
SCHEMBL411 0.87
SCHEMBL5760792 0.87
SCHEMBL15013516 0.82
Ammonia Solution, Strong SCHEMBL170117 0.82
Phosphine SCHEMBL5862962 0.82
SCHEMBL1434105 0.82
Iodide SCHEMBL20502819 0.82
Bromide SCHEMBL1521338 0.82
SCHEMBL1486799 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9394338-B2 Glutathione analogs and uses thereof REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2016-07-19 US disclosed
US-20140154192-A1 GLUTATHIONE ANALOGS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2014-06-05 US disclosed
EP-2729483-A1 GLUTATHIONE ANALOGS AND USES THEREOF Regents Of The University Of Minnesota (US) 2014-05-14 EP disclosed
WO-2013009647-A1 GLUTATHIONE ANALOGS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2013-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140154192-A1 GLUTATHIONE ANALOGS AND USES THEREOF GPX1, GSR, GSTA1 TSHR 2426/4885ALDH1A1 281/4885TRPA1 2139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.