Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16216046 | 1.00 | THRA (0.33) | THRATHRB | |
| SCHEMBL10580160 | 0.77 | — | — | |
| SCHEMBL10578635 | 0.77 | — | — | |
| SCHEMBL2945094 | 0.76 | — | — | |
| SCHEMBL21001053 | 0.74 | THRA (0.31) | THRATHRB | |
| SCHEMBL27687217 | 0.73 | — | — | |
| SCHEMBL24448815 | 0.73 | CNR2 (0.38) | THRATHRB | |
| SCHEMBL24448889 | 0.73 | SIGMAR1 (0.31) | — | |
| SCHEMBL24448790 | 0.73 | SIGMAR1 (0.31) | — | |
| SCHEMBL14646723 | 0.73 | CNR2 (0.38) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773869-B9 | MACROCYCLIC MODULATORS OF THE GHRELIN RECEPTOR | TRANZYME PHARMA INC (CA) | 2013-01-23 | — | — | EP | disclosed |